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KMID : 1143620160200010042
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Korean Journal of Nuclear Medicine Technology
2016 Volume.20 No. 1 p.42 ~ p.46
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Study on the Usefulness about Molecular Breast Imaging In Dense Breast
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Baek Song-Ee
Kang Chun-Koo
Lee Han-Wool
Park Min-Soo
Choi Young-Sook
Kim Jae-Sam
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Abstract
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Purpose : Mammography is the most widely used scan for the early diagnosis since it is possible to observe the anatomy
of the breast. however, The sensitivity is markedly reduced in high-risk patients with dense breast. Molecular Breast Imaging (MBI) sacn is possible to get the high resolution functional imaging, and This new neclear medicine technique get the more improved diagnostic information through It is useful for confirmation of tumor's location in dense breast. The purpose of this study is to evaluate the usefulness of MBI for tumor diagnosis in patients with dense breast.
Materials and Methods : We investigated 10 patients female breast cancer with dense breast type who had visited the hospital from September 1st to Octorber 10th, 2015. The patients underwent both MBI and Mammography. MBI (Discovery
750B; General Electric Healthcare, USA) scan was 99mTc-MIBI injected with 20 mCi on the opposite side of the arm with the lesions, after 20 minutes, gained bilateral breast CC (CranioCaudal), MLO (Medio Lateral Oblique) View. Mammography was also conducted in the same posture. MBI and Mammography images were compared to evaluate the sensitivity and specificity of each case utilizing both image and two images in blind tests.
Results : The results of the blind test for breast cancer showed that the sensitivity of Mammography, MBI scan was 63%,
89%, respectively, and that their specificity was 38%, 87%, respectively. Using both the Mammography and
MBI scan was Sensitivity 92%, specificity 90%.
Conclusion : This research has found that, The tumor of dense tissue that can not easily distinguishable in Mammography is possible to more accurate diagnosis since It is easy to visually evaluation. But MBI sacn has difficulty imaging
microcalcificatons, If used in conjunction with mammography it is thought to give provide more diagnostic
information.
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KEYWORD
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Molecular Breast Imaging, 99mTc-MIBI, Dense breast, Breast cancer
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